In 1999 a good friend loaned me "The Miracle of MSM" that was written by two research physicians.
Within 24 hours I noticed an increase in physical energy.
Within a few days I was going through the typical symptoms of detoxification exactly as the book explained would happen. Over the next year or two my allergies decreased greatly in severity. Muscle and back pain decreased. The incidence of cold and flu decreased greatly and I stopped getting the annual case of bronchitis that had followed a bout of pheumonia that I had, (I think it was back in 1996 or 1997)?
This webpage is a summary of the book and from my own experience is accurate.
Cell Membrane Permeability